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Aberrant topological patterns of brain structural network in temporal lobe epilepsy
Author(s) -
Yasuda Clarissa Lin,
Chen Zhang,
Beltramini Guilherme Coco,
Coan Ana Carolina,
Morita Marcia Elisabete,
Kubota Bruno,
Bergo Felipe,
Beaulieu Christian,
Cendes Fernando,
Gross Donald William
Publication year - 2015
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/epi.13225
Subject(s) - temporal lobe , neuroscience , hippocampus , epilepsy , psychology , amygdala , hippocampal formation , audiology , medicine
Although altered large-scale brain network organization in patients with temporal lobe epilepsy (TLE) has been shown using morphologic measurements such as cortical thickness, these studies, have not included critical subcortical structures (such as hippocampus and amygdala) and have had relatively small sample sizes. Here, we investigated differences in topological organization of the brain volumetric networks between patients with right TLE (RTLE) and left TLE (LTLE) with unilateral hippocampal atrophy.