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Progressive fiber tract affections after temporal lobe surgery
Author(s) -
Faber Jennifer,
SchoeneBake JanChristoph,
Trautner Peter,
Lehe Marec,
Elger Christian E.,
Weber Bernd
Publication year - 2013
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/epi.12077
Subject(s) - temporal lobe , fiber tract , diffusion mri , medicine , white matter , surgery , epilepsy , lobe , anatomy , radiology , magnetic resonance imaging , psychiatry
Summary Several studies reported changes in white matter architecture following temporal lobe surgery in patients with temporal lobe epilepsy ( TLE ) at short intervals after surgery. We investigated 20 patients with left‐sided TLE using diffusion‐imaging at two time points, that is, at 3–6 months and 12 months after surgery, to investigate postsurgical plasticity. We observed a loss of fiber tract integrity mainly in fiber tracts of the ipsilateral temporal lobe. Our data show that the remodeling of brain connectivity after surgical interventions continues for longer time periods. The functional implications of these plastic changes will have to be explored.