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Chlorhexidine release from orthodontic adhesives after topical chlorhexidine treatment
Author(s) -
Lim BumSoon,
Cheng Yanping,
Lee SeungPyo,
Ahn SugJoon
Publication year - 2013
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/eos.12033
Subject(s) - chlorhexidine , saliva , adhesive , chemistry , glass ionomer cement , dentistry , nuclear chemistry , adsorption , distilled water , chromatography , medicine , organic chemistry , biochemistry , layer (electronics)
This study was designed to investigate the ability of orthodontic adhesives to adsorb and release chlorhexidine ( CHX ) after periodic treatment with 1% CHX solution. Composite and resin‐modified glass‐ionomer cement ( RM ‐ GIC ) adhesive disks were incubated with whole saliva or distilled water for 2 h. Release of CHX was measured using high‐performance liquid chromatography after 1, 2, and 5 d of incubation, 1 min after exposure to 1% CHX solution. The CHX measurements were performed in a 5‐d cycle, which was repeated four consecutive times ( n = 7). The amount of CHX adsorbed and the cumulative amounts of CHX released, with respect to type of adhesive and saliva‐coating, were analyzed using repeated‐measures anova . Chlorhexidine‐adsorbed orthodontic adhesives demonstrated a short‐term release of CHX , which rapidly returned to near‐baseline levels within 3 d. Saliva‐coating did not significantly influence CHX release from RM ‐ GIC , but increased the amount of CHX released from the composite. The amount of CHX released from the composite was 20‐fold higher than that released from the RM ‐ GIC after saliva‐coating. The composite adhesive showed a greater adsorption capacity for CHX than did the RM ‐ GIC , which was more evident after saliva‐coating. This study suggests that composite adhesives may be a significantly more effective CHX reservoir than RM ‐ GIC s in the oral cavity filled with saliva.