English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Background and purpose  Lithuania is one of the countries with the highest incidence of tick‐borne encephalitis ( TBE ) in Europe. The aim of this study was to describe the epidemiological patterns of  TBE  in Lithuania, and characterize clinical features in adults in the light of the high incidence in recent years.    Methods  Surveillance data available on the website of the Centre for Communicable Diseases and  AIDS  of Lithuania were used to describe the epidemiological patterns of  TBE . The retrospective study included 712 patients hospitalized in the Centre for Infectious Diseases and the Centre for Neurology of Vilnius University in the years 2005–2014.    Results  Tick‐borne encephalitis incidence rates have been increasing by 8.5% per year for the 45‐year period from 1970 to 2014. The joinpoint model finds two joinpoints at 1991 and 1994, with a significant decrease of 8.4% per year ( P  < 0.05) prior to the joinpoint at 1991, and a rise of 195.2% afterwards.  TBE  presented with meningoencephalitis in 556 cases (81.3%). A total of 129 patients (18%) had a severe case of the disease. The most common neurological signs were ataxia (579, 81.3%), meningeal signs (474, 66.5%) and tremor (338, 47.5%). Limb paresis was observed in 6.3% of patients. Five patients (0.7%) died, and 544 patients (76.7%) were discharged with sequelae.    Conclusions  Intensified efforts in promoting  TBE  vaccination will be needed in the light of the high incidence and expanded spatial distribution. Significant prognostic factors for severe cases of the disease were age above 61 and delayed immune response of specific immunoglobulin G.

european journal of neurology

Epidemiological patterns of tick‐borne encephalitis in Lithuania and clinical features in adults in the light of the high incidence in recent years: a retrospective study