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Non‐invasive brain stimulation for dystonia: therapeutic implications
Author(s) -
Erro R.,
Tinazzi M.,
Morgante F.,
Bhatia K. P.
Publication year - 2017
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/ene.13363
Subject(s) - dystonia , deep brain stimulation , medicine , neuroscience , brain stimulation , pathophysiology , movement disorders , physical medicine and rehabilitation , stimulation , psychology , pathology , disease , parkinson's disease
Dystonia is characterized by excessive muscle contractions giving rise to abnormal posture and involuntary twisting movements. Although dystonia syndromes are a heterogeneous group of disorders, certain pathophysiological mechanisms have been consistently identified across different forms. These pathophysiological mechanisms have subsequently been exploited for the development of non‐invasive brain stimulation ( NIBS ) techniques able to modulate neural activity in one or more nodes of the putative network that is altered in dystonia, and the therapeutic role of NIBS has hence been suggested. Here all studies that applied such techniques as a therapeutic intervention in any forms of dystonia, including the few works performed in children, are reviewed and emerging concepts and pitfalls of NIBS are discussed.