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Subthalamic deep brain stimulation effects on odor identification in P arkinson's disease
Author(s) -
Fabbri M.,
Guedes L. C.,
Coelho M.,
Simão D.,
Abreu D.,
Rosa M. M.,
SilveiraMoriyama L.,
Ferreira J. J.
Publication year - 2015
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/ene.12396
Subject(s) - deep brain stimulation , subthalamic nucleus , medicine , parkinson's disease , olfactory system , olfaction , odor , stimulation , disease , neuroscience , audiology , psychiatry , psychology
Background and purpose Olfactory dysfunction is common in Parkinson's disease ( PD ) and it is one of the earliest non‐motor symptoms. A few studies have suggested that deep brain stimulation of the subthalamic nucleus ( STN ‐ DBS ) could improve olfactory function. Our aim was to evaluate the acute effect of bilateral STN ‐ DBS on a commonly used smell test in PD patients. Methods Fifteen PD patients who underwent bilateral STN ‐ DBS and 15 controls were recruited. Patients and controls were tested for odor identification. Results No statistical differences were documented between ON and OFF STN ‐ DBS acute stimulation concerning olfaction. Controls presented a better performance for olfactory identification than patients. Conclusions Our exploratory study did not support that bilateral STN ‐ DBS could have an acute effect on olfactory function in PD patients.