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Subthreshold depression and subjective cognitive complaints in P arkinson's disease
Author(s) -
Santangelo G.,
Vitale C.,
Trojano L.,
Angrisano M. G.,
Picillo M.,
Errico D.,
Agosti V.,
Grossi D.,
Barone P.
Publication year - 2014
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/ene.12219
Subject(s) - depression (economics) , medicine , cognition , effects of sleep deprivation on cognitive performance , disease , depressive symptoms , psychiatry , clinical psychology , physical therapy , economics , macroeconomics
Background and purpose Subthreshold depression (Sub D ) is characterized by clinically relevant depressive symptoms not meeting criteria for major depression. The possible association of S ub D with subjective cognitive complaints and/or objective cognitive impairments was investigated in a sample of consecutive, non‐demented P arkinson's disease ( PD ) outpatients. Methods Amongst 115 patients, S ub D was identified in 30 patients, major depression in 33; 36 patients were classified as non‐depressed. Enrolled patients were administered tests and questionnaires validated in PD for assessing objective and subjective cognitive dysfunctions. Results On objective cognitive measures S ub D patients did not differ from non‐depressed patients, whereas depressed patients achieved significantly lower scores than the other two groups. S ub D and depressed patients reported more cognitive complaints than non‐depressed patients. Conclusions S ub D is a non‐motor aspect of PD that is not related to objective cognitive deficits but is associated with subjective cognitive complaints, thus impacting on patients’ well‐being.