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Stroke recurrence in patients with recently symptomatic carotid stenosis and scheduled for carotid revascularization
Author(s) -
AlKhaled M.,
Awwad H.,
Matthis C.,
Eggers J.
Publication year - 2013
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/ene.12078
Subject(s) - medicine , stroke (engine) , stenosis , revascularization , ischaemic stroke , acute stroke , cardiology , surgery , ischemia , mechanical engineering , myocardial infarction , tissue plasminogen activator , engineering
Background and purpose Patients with symptomatic carotid stenosis (s CS ) have a higher risk of stroke recurrence following the first ischaemic event. Guidelines recommend that patients undergo carotid revascularization ( CR ), preferably within 2 weeks of the event. We aimed to determine the rate of stroke recurrence during hospitalization in patients who were admitted to the hospital with an acute ischaemic event and who underwent CR for recently s CS . Methods As part of the stroke registry in S chleswig‐ H olstein, G ermany ( Q ug SS 2; Qualitätsgemeinschaft S chlaganfallversorgung in S chleswig‐ H olstein), over a 4.5‐year period (starting 2007) all patients ( N = 15 797) who were admitted to the hospital with an acute cerebral ischaemic event were included and prospectively evaluated. Results A total of 597 (3.8%) patients (mean age, 71 ± 10 years; 30% women) underwent a CR . The median time between symptom onset and admission to hospitals was 6 h. During the mean hospitalization of 10 days, 30 patients (5%) suffered a stroke. The rates of stroke recurrence were higher, albeit non‐significantly, in men compared with women (6% vs. 2.3%, respectively; P = 0.059), and in patients admitted with ischaemic stroke compared with patients admitted with transient ischaemic attack (6.1% vs. 2%, respectively; P = 0.052). The risk of stroke recurrence did not show any association with the other demographic and clinical parameters. Conclusion The rate of stroke recurrence was 5% in patients with recently s CS who scheduled for CR . This suggests that CR should be performed immediately after presenting event to prevent stroke recurrence.