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Abnormalities in FGF family members and their roles in modulating depression‐related molecules
Author(s) -
Xu YuHao,
Zhu Yan,
Zhu YuanYuan,
Wei Hong,
Zhang NingNing,
Qin JiaSheng,
Zhu XiaoLan,
Yu Ming,
Li YueFeng
Publication year - 2021
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/ejn.14570
Subject(s) - depression (economics) , fibroblast growth factor , psychology , neuroscience , medicine , psychiatry , receptor , economics , macroeconomics
The role of the fibroblast growth factor ( FGF ) system in depression has received considerable attention in recent years. To understand the role of this system, it is important to identify the specific members of the FGF family that have been implicated and the various mechanisms that they modulated. Here, we review the role of FGF s in depression and integrate evidence from clinical and basic research. These data suggest that changes in the FGF family are involved in depression and possibly in a wider range of psychiatric disorders. We analyse the abnormalities of FGF family members in depression and their roles in modulating depression‐related molecules. The role of the FGF family in depression and related disorders needs to be studied in more detail.