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Pathological Gambling in Parkinson's disease: Autonomic measures supporting impaired decision‐making
Author(s) -
Angioletti Laura,
Siri Chiara,
Meucci Nicoletta,
Pezzoli Gianni,
Balconi Michela
Publication year - 2019
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/ejn.13993
Subject(s) - iowa gambling task , psychology , pathological , parkinson's disease , arousal , impulse control disorder , autonomic nervous system , skin conductance , disease , developmental psychology , addiction , audiology , heart rate , clinical psychology , psychiatry , neuroscience , medicine , cognition , blood pressure , biomedical engineering
According to the somatic marker hypothesis, autonomic measures and arousal modulation can reveal a difference in subgroups of patients developing impaired decision‐making because of addictions. Previously, pathological gambling ( PG ) and Parkinson's disease ( PD ) have been associated with differential arousal levels during gambling behavior. However, no research considered the specific autonomic responses of Parkinson's disease patients with pathological gambling and with a previous history of gambling. Thus, this study investigated skin conductance responses ( SCR s), skin conductance level ( SCL ) and heart rate ( HR ) during the Iowa Gambling Task ( IGT ) in two groups of PD patients with gambling disorder, active ( PD Gamblers; n = 14) or remitted ( PD Non‐Gamblers; n = 13) and a control group of patients with Parkinson's disease only ( n = 13). Anticipatory autonomic responses to disadvantageous decks and advantageous decks during the Iowa Gambling Task were measured for each participant. The PD Gamblers group performed worse than the PD Non‐Gamblers and the control groups at the IGT task and exhibited lower SCR s, SCL , and HR during the decision‐making processing of cards belonging to disadvantageous decks. The role of autonomic and behavioral measures was considered.