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Issue Cover (July 2014)
Publication year - 2014
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1111/ejn.12693
Subject(s) - nicotinic agonist , zebrafish , acetylcholine receptor , nicotine , neuroscience , embryonic stem cell , acetylcholine , nicotinic acetylcholine receptor , embryo , biology , receptor , microbiology and biotechnology , pharmacology , genetics , gene
Cover Illustration: Photomicrographs of embryonic zebrafish (20, 22, and 25 hours post fertilization) highlight the rapid development of this organism . During this time, the locomotor apparatus of the embryo is becoming functional. Zebrafish embryos exposed to nicotine exhibit a robust motor output which is mediated by activation of neuronal nicotinic acetylcholine receptors (nAChRs). In general, neuronal nAChRs are comprised of α and β subunits. For details, see the article of Menelaou et al . ( Activation of α2A‐containing nicotinic acetylcholine receptors mediates nicotine‐induced motor output in embryonic zebrafish. Eur. J. Neurosci ., 40 , 2225–2240).