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Prospective memory in individuals with first‐episode schizophrenia: A two‐year longitudinal study
Author(s) -
Cheung Eric F. C.,
Lui Simon S. Y.,
Wang Ya,
Liu Amy C. Y.,
Chui William W. H.,
Yeung Hera K. H.,
Yang TianXiao,
Shum David H. K.,
Chan Raymond C. K.
Publication year - 2019
Publication title -
early intervention in psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.087
H-Index - 45
eISSN - 1751-7893
pISSN - 1751-7885
DOI - 10.1111/eip.12733
Subject(s) - schizophrenia (object oriented programming) , longitudinal study , psychology , repeated measures design , analysis of variance , prospective cohort study , psychiatry , medicine , statistics , mathematics , pathology
Aim The present study aimed to explore the two‐year naturalistic trajectory of time‐ and event‐based prospective memory (PM) in patients with first‐episode schizophrenia. Methods We administered a computer‐based dual‐task PM paradigm to 57 individuals with first‐episode schizophrenia at baseline and after 6 months, 12 months and 24 months. Forty‐eight healthy controls were also recruited and completed all the measures at baseline. We compared the trajectories between time‐based and event‐based PM in first‐episode schizophrenia patients using repeated measures ANOVAs, and examined the relationship between PM and clinical symptoms using Spearman's correlation. Results PM impairments improved significantly after 24 months of follow‐up. However, time‐based and event‐based PM appeared to run different trajectories. After 24 months, first‐episode schizophrenia patient performed poorer than healthy controls in time‐based but not event‐based PM. PM did not appear to be correlated with clinical symptoms, both cross‐sectionally and longitudinally. Conclusions This is one of the longest follow‐up studies investigating PM in first‐episode schizophrenia. Our results provide evidence to support that time‐based PM is more temporally stable than event‐based PM.