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Open‐label study of cognitive behavioural therapy for individuals with at‐risk mental state: Feasibility in the Japanese clinical setting
Author(s) -
Matsumoto Kazunori,
Ohmuro Noriyuki,
Tsujino Naohisa,
Nishiyama Shimako,
Abe Koichi,
Hamaie Yumiko,
Katsura Masahiro,
Inoue Naomi,
Matsuoka Hiroo,
Kawasaki Yasuhiro,
Kishimoto Toshifumi,
Suzuki Michio,
Mizuno Masafumi
Publication year - 2019
Publication title -
early intervention in psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.087
H-Index - 45
eISSN - 1751-7893
pISSN - 1751-7885
DOI - 10.1111/eip.12541
Subject(s) - intervention (counseling) , at risk mental state , positive and negative syndrome scale , cognition , medicine , schizophrenia (object oriented programming) , psychiatry , cognitive behavioral therapy , clinical trial , clinical psychology , psychosis , psychology
Aim To date, most cognitive behavioural therapy (CBT) trials for individuals with at‐risk metal state (ARMS) have been conducted in few Western countries and its feasibility in other regions, including Japan, has not been established. Methods We designed an open‐label pilot study. Fourteen ARMS participants received CBT over 6 months and were followed‐up for 6 months. Results Thirteen individuals completed the CBT intervention and assessments. The mean total score on the Positive and Negative Syndrome Scale improved from 60.2 to 46.0 after the intervention (Cohen's d = 1.1). The effects were maintained at the follow‐up assessment. One participant transitioned to psychosis after the CBT intervention, and was the only patient who received antipsychotics. Conclusions We confirmed the feasibility of the provision of CBT for ARMS in Japan. Since overprescription of antipsychotics is a matter of great concern in Japan, CBT could be a valuable alternative treatment strategy.

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