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Negative symptoms and impaired social functioning predict later psychosis in L atino youth at clinical high risk in the N orth A merican prodromal longitudinal studies consortium
Author(s) -
Alderman Tracy,
Addington Jean,
Bearden Carrie,
Can Tyrone D.,
Cornblatt Barbara A.,
McGlashan Thomas H.,
Perkins Diana O.,
Seidman Larry J.,
Tsuang Ming T.,
Walker Elaine F.,
Woods Scott W.,
Cadenhead Kristin S.
Publication year - 2015
Publication title -
early intervention in psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.087
H-Index - 45
eISSN - 1751-7893
pISSN - 1751-7885
DOI - 10.1111/eip.12128
Subject(s) - prodrome , psychosis , psychology , clinical psychology , schizophrenia (object oriented programming) , ethnic group , longitudinal study , psychiatry , social support , medicine , pathology , sociology , anthropology , psychotherapist
Aim Examining ethnically related variables in evaluating those at risk for psychosis is critical. This study investigated sociodemographic and clinical characteristics of L atino versus non‐ L atino clinical high‐risk ( CHR ) subjects and healthy control ( HC ) subjects in the first N orth A merican Pr odrome L ongitudinal S tudy. Methods Fifty‐six L atino CHR subjects were compared to 25 L atino HC and 423 non‐ L atino CHR subjects across clinical and demographic variables. Thirty‐nine of the 56 CHR subjects completed at least one subsequent clinical evaluation over the 2.5‐year period with 39% developing a psychotic illness. Characteristics of L atino CHR subjects who later converted to psychosis (‘converters’) were compared to those who did not (‘non‐converters’). Results L atino CHR subjects were younger than non‐ L atino CHR subjects and had less education than L atino HC subjects and non‐ L atino CHR counterparts. L atino CHR converters had higher scores than L atino non‐converters on the S tructured I nterview for P rodromal S yndromes total negative symptoms that were accounted for by decreased expression of emotion and personal hygiene/social attentiveness subsections. L atino CHR converters scored lower on the global functioning:social scale, indicating worse social functioning than L atino non‐converters. Conclusion Based on this sample, L atino CHR subjects may seek treatment earlier and have less education than non‐ L atino CHR subjects. Deficits in social functioning and impaired personal hygiene/social attentiveness among L atino CHR subjects predicted later psychosis and may represent important areas for future study. Larger sample sizes are needed to more thoroughly investigate the observed ethnic differences and risk factors for psychosis in L atino youth.