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Predictors of substance use reduction in an epidemiological first‐episode psychosis cohort
Author(s) -
Rebgetz Shane,
Conus Philippe,
Hides Leanne,
Kavanagh David J.,
Cotton Sue,
Schimmelmann Benno G.,
McGorry Patrick D.,
Lambert Martin
Publication year - 2014
Publication title -
early intervention in psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.087
H-Index - 45
eISSN - 1751-7893
pISSN - 1751-7885
DOI - 10.1111/eip.12067
Subject(s) - psychiatry , cohort , psychosis , epidemiology , logistic regression , cannabis , medicine , clinical psychology , psychology
Abstract Aim To assess the predictors of a significant decrease or cessation of substance use ( SU ) in a treated epidemiological cohort of first‐episode psychosis ( FEP ) patients. Method Participants were FEP patients of the E arly P sychosis P revention and I ntervention C entre in A ustralia. Patients' medical files were reviewed using a standardized file audit. Data on 432 patients with FEP and baseline co‐morbid substance use disorder ( SUD ) were available for analysis. Predictors of reduction/cessation of SU at follow up were examined using logistic regression analyses. Results In univariate analyses, a reduction/cessation of SU was predicted by baseline measures reflecting higher education, employment, accommodation with others, cannabis use disorder ( CUD ) only (rather than poly‐SUDs), better global functioning and better premorbid social and occupational functioning, later age at onset of psychosis, and a diagnosis of non‐affective psychosis. In multivariate analysis, CUD alone and better premorbid social and occupational functioning remained significant predictors. Conclusions Addressing SUDs and social and occupational goals in people with FEP may offer opportunities to prevent SUDs becoming more severe or entrenched. Further longitudinal research on recovery from SU and FEP is needed to disentangle directions of influence and identify key targets for intervention.