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A Western dietary pattern is associated with elevated level of high sensitive C‐reactive protein among adolescent girls
Author(s) -
Khayyatzadeh Sayyed Saeid,
Bagherniya Mohammad,
Fazeli Mostafa,
Khorasanchi Zahra,
Bidokhti Mina Safari,
Ahmadinejad Malihe,
Khoshmohabbat Somaieh,
Arabpour Mahla,
Afkhamizadeh Mozhgan,
Ferns Gordon A.,
Masoudifar Maryam,
GhayourMobarhan Majid
Publication year - 2018
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/eci.12897
Subject(s) - c reactive protein , medicine , confounding , food frequency questionnaire , logistic regression , cross sectional study , physiology , inflammation , pathology
Background Serum high sensitive C‐reactive protein (hs‐CRP), is an indicator of low‐grade inflammation, and is associated with several non‐communicable diseases. The effects of diet on inflammation have not been extensively investigated, particularly among adolescents. We aimed to examine the association between major dietary patterns and elevated serum level of hs‐CRP among Iranian adolescent girls. Materials and methods In this cross‐sectional study, a total of 670 adolescent girls were recruited from several schools in different areas of Mashhad and Sabzevar cities, Iran. The dietary intakes of study participants were collected using a 147‐item food frequency questionnaire. To identify major dietary patterns based on the 40 food groups, we used principal component analysis. Serum concentration of hs‐CRP was measured using commercial kits and the BT‐3000 auto‐analyser. To investigate the association between dietary patterns and elevated serum level of hs‐CRP, we used logistic regression analysis. Results Three specific dietary patterns were identified: (i) healthy, (ii) traditional and (iii) western dietary patterns. A significant association was found between more adherence to Western dietary pattern and elevated serum level of hs‐CRP (OR: 1.58; 95% CI: 1.02‐2.42, P ‐trend = .03); these association remained significant after adjustment for potential confounders. However, there was no significant relationship between healthy and traditional dietary patterns and elevated serum level of hs‐CRP .Conclusion Our results indicate that there is a significant positive association between more adherence to Western dietary pattern and higher serum levels of hs‐CRP among Iranian adolescent girls. Further studies, particularly longitudinal intervention studies may be required to clarify these relationships.