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Myocardial strain pattern progress in patients with Coarctation of the Aorta undergoing aortic stenting
Author(s) -
Aragão Natalia Freitas de Deus Vale,
Borgo Juliaicchio Valentim,
Jesus Carlos Alberto de,
Davoglio Tathiane,
Armstrong Anderson da Costa,
Barretto Rodrigo Bellio de Mattos,
Le Bihan David,
Assef Jorge Eduardo,
Pedra Carlos Augusto Cardoso,
Pedra Simone Rolim Fernandes Fontes
Publication year - 2021
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.14937
Subject(s) - medicine , cardiology , speckle tracking echocardiography , ejection fraction , subclinical infection , percutaneous coronary intervention , coarctation of the aorta , stent , aorta , heart failure , myocardial infarction
Background and Aim Ventricular function evaluation in coarctation of the aorta (CoA) has become more sophisticated and precise with speckle tracking, revealing subclinical changes. However, CoA stenting treatment effects in on myocardial strain are still controversial. This study aimed to estimate the extent to which changes in left ventricular global longitudinal strain (LV GLS) occur in patients with CoA who undergo stenting. Methods The study included 21 patients with CoA (median age: 15 years [8–39]) and 21 healthy individuals matched by age and gender. Clinical and echocardiographic evaluations were performed 1 day before, 6 months, and 1 year after stenting. Correlations between LV GLS and arm‐leg gradient, isthmus gradient on echocardiogram, age at intervention, left ventricular mass, and ejection fraction were tested. Results Before treatment, patients with CoA had lower LV GLS than the control group (−18.4% ± 1.96 vs −21.5% ± 1.37; P < .01), showing significant increase to −19.4% ± 2.1 at 6 months and −20.7% ± 2.19 at 1 year, P < .001. Only 28.5% (6 patients) had preserved GLS before treatment, improving to 80.9% (17 patients) in 1 year. The only variable correlated with low LV GLS values before treatment was age at intervention (Spearman's index = −0.571; P = .007). Conclusion Percutaneous therapy showed significant LV GLS improvement 12 months after aortic stenting. Older patients have lower GLS, suggesting that early intervention may have positive effects on preservation of LV systolic function.