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Echocardiographic assessment of left ventricular function recovery post percutaneous coronary intervention of chronic total occlusions in patients with low and mid‐range left ventricular ejection fractions
Author(s) -
Samy Mohamed,
El Awady Waleed Salem,
AlDaydamony Mohammad Mustafa,
Abd El Samei Magdy Mohammad,
Shokry Khaled Abd El Azim
Publication year - 2020
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.14582
Subject(s) - ejection fraction , medicine , cardiology , percutaneous coronary intervention , conventional pci , cardiac catheterization , cardiac function curve , heart failure , myocardial infarction
Abstract Objectives Coronary chronic total occlusion (CTO) is a frequent condition encountered in cardiac catheterization laboratory with a prevalence of about 20%. Through literature, data are scarcely reported regarding the left ventricular (LV) function recovery post CTO percutaneous coronary intervention (PCI) in patients with low (<40%) and mid‐range (40%‐49%) LV ejection fraction (LVEF). The aim of this study was to assess the echocardiographic outcomes of CTO patients with low and mid‐range LVEF successfully revascularized at 6‐month follow‐up. Methods This prospective study included 75 patients with at least one CTO of an epicardial coronary artery proved by previous diagnostic coronary angiography with PCI attempt indication, and successfully revascularized. They were equally divided according to LVEF into three groups, and echocardiographic remodeling indices were assessed at baseline and 6 months post PCI. Results Our study showed significant improvement of LVEF, S‐wave velocity by tissue doppler imaging (TDI), LV wall‐motion score (LVWMS), and LV systolic sphericity index (LVSIS) 6 months post CTO PCI in low LVEF group, and a significant improvement in LVEF, S‐wave velocity, and LVWMS in mid‐range LVEF group ( P  < .05). The delta change in LVEF was significantly more in low LVEF group, compared to the other two groups ( F  = 4.739, P  < .05). Conclusion Successful CTO PCI in patients with low and mid‐range LVEF is associated with significant improvement of LVEF and other indices of myocardial remodeling after 6 months of follow‐up.

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