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Presystolic wave is associated with carotid intima media thickness
Author(s) -
Kul Selim,
Dursun İhsan,
Sayın Muhammet Raşit,
Şahin Sinan,
Turan Turhan,
Akyüz Ali Rıza,
Korkmaz Levent,
Karadeniz Ayşegül,
Yılmaz Ahmet Seyda,
Durmuş İsmet
Publication year - 2019
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.14217
Subject(s) - medicine , dyslipidemia , cardiology , ventricle , intima media thickness , diabetes mellitus , body mass index , correlation , disease , carotid arteries , endocrinology , geometry , mathematics
Carotid intima media thickness (CIMT), a direct marker of atherosclerosis, has emerged as a promising means for cardiovascular risk evaluation. Presystolic wave (PSW) is commonly detected by the Doppler interrogation of the left ventricular outflow tract (LVOT). It is thought to be a result of a stiff left ventricle and impaired LV compliance. Herein, we aimed to investigate a possible association between carotid intima media thickness, an atherosclerotic marker, and PSW. Method We prospectively enrolled 282 patients divided into two groups based on the presence of PSW: 221 (89F; mean age: 49.3 ± 11.5 years) had PSW on Doppler examination while 61 patients (32F; mean age: 46.4 ± 10.3 years) did not. Both groups were compared with respect to demographic, clinical properties, and CIMT. Results Both groups had comparable age, body mass index, and diabetes mellitus, hypertension, dyslipidemia, smoking, and family history for coronary heart disease. PSW‐positive group had significantly higher CIMT (PSW‐positive: 0.59 ± 0.22 mm vs PSW‐negative: 0.42 ± 0.11 mm; P < 0.001) than PSW‐negative group. Multivariate analysis showed that the independent predictors of increased CIMT were age (95% CI; 1.044–1.101, P < 0.001), dyslipidemia (95% CI; 0.147–0.664, P = 0.002), and the presence of PSW (95% CI; 2.168–7.836, P < 0.001).Correlation analysis showed that PSW velocity is correlated with increased CIMT in PSW‐positive group ( r : 0.418, P < 0.001). Conclusion Assessment of PSW on TTE is easy and feasible method. Presence of PSW and increased PSW velocity on TTE might provide information that we should be careful in terms of subclinical atherosclerosis.