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Valvular involvement in granulomatosis with polyangiitis: Case report and systematic review of literature
Author(s) -
AlHabbaa Ahmed,
Rawla Prashanth,
Morra Mostafa Ebraheem,
Abotaha Ahmed Ahmed,
Sakr Eman ElSayed,
Abdo Shehata Mostafa Ahmed,
Shahin Karim Mohamed,
Abdel Mageed Sarah,
Huy Nguyen Tien
Publication year - 2018
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.14094
Subject(s) - granulomatosis with polyangiitis , medicine , lesion , cardiology , tricuspid valve , mitral valve , aortic valve , radiology , surgery , vasculitis , disease
Background Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition; however, patients with GPA rarely experience endocardial valve lesions. Methods We report a GPA case with tricuspid valve destruction together with a systematic review to highlight the characteristics of all previously reported GPA cases with valvular involvement. Results Among 36 cases included, the aortic valve was involved in 15 (41.7%) cases while the mitral valve was involved in 9 (25%) subjects. Combined lesion of both aortic and mitral valves was reported in 9 (25%) patients. Conclusion We recommend routine echocardiography examination to rule out any cardiac valve lesion once GPA is suspected.