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Left atrial volume and function in patients with cardiac syndrome X assessed by real time three‐dimensional echocardiography
Author(s) -
Acıkgoz Nusret,
Yagmur Julide,
Kurtoglu Ertugrul,
Ermis Necip,
Cansel Mehmet
Publication year - 2017
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.13534
Subject(s) - medicine , cardiology , ejection fraction , stroke volume , cardiac syndrome x , speckle tracking echocardiography , diastole , myocardial infarction , blood pressure , heart failure , angina
Objective The aim of this study was to evaluate left atrial ( LA ) volume and function using real time three‐dimensional echocardiography ( RT 3 DE ) in patients with cardiac syndrome X ( CSX ). Methods Fifty patients with CSX (28 females; mean age 50.9±10.9 years) and 50 age‐ and gender‐matched healthy controls (30 females; mean age 52.3±9.8 years) who had negative treadmill exercise test and normal coronary arteries on invasive coronary angiography were included in the study. Comprehensive two‐dimensional (2D), pulsed and tissue Doppler, speckle tracking echocardiography, and RT 3 DE for the assessment of LA dynamics were performed in all study participants. Results Cardiac syndrome X and control groups have similar clinical characteristics regarding age, sex, body mass index, hypertension, diabetes, and smoking habit. 2D echocardiographic parameters were also similar between groups. Pulsed‐ and tissue Doppler parameters, IVRT , A , and A m values, were higher in CSX group, while E m , E / A , and E m / A m ratios were higher in the control group reflecting mild diastolic dysfunction. Regarding RT 3 DE parameters, LA maximum volume, minimum volume, volume before atrial contraction, LA maximum volume index, total and active stroke volumes were found to be increased in CSX patients. However, LA total stroke fraction, passive stroke volume, passive stroke fraction, peak systolic, and diastolic longitudinal strains were found to be lower in CSX patients. Conclusion The main finding of this study was that CSX patients had altered LA booster pump, reservoir, and conduit functions. This finding may have clinical implications for early detection of abnormal LA dynamics in CSX patients.