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Evaluation of left ventricular function in preterm infants with bronchopulmonary dysplasia using various echocardiographic techniques
Author(s) -
Bokiniec Renata,
Własienko Paweł,
BorszewskaKornacka Maria,
SzymkiewiczDangel Joanna
Publication year - 2017
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.13488
Subject(s) - bronchopulmonary dysplasia , medicine , dysplasia , cardiology , gastroenterology , gestational age , pregnancy , genetics , biology
Aim Echocardiographic evaluation of left ventricular function in preterm infants with and without bronchopulmonary dysplasia. Methods In 82 preterm infants (32 in no‐bronchopulmonary‐dysplasia group, 35 in mild‐bronchopulmonary‐dysplasia group, and 15 in severe‐bronchopulmonary‐dysplasia group), echocardiography was performed on the first day of life, at 28 days of life, and at 36 weeks postconceptional age. Results The mean E/A ratio at 36 PCA was 0.94±0.31 and 0.73±0.12 in the mild‐ and severe‐bronchopulmonary‐dysplasia groups, respectively ( P =.037). The mean E′‐wave velocity was 5.62±1.61 cm/s vs 4.32±1.11 cm/s at 1 day of life ( P =.006) and 6.40±1.39 cm/s vs 5.34±1.37 cm/s at 28 days of life ( P =.030) in the no‐bronchopulmonary‐dysplasia and mild‐bronchopulmonary‐dysplasia groups, respectively. This measure tended to be lower in the severe‐bronchopulmonary‐dysplasia group compared to the no‐bronchopulmonary‐dysplasia group (5.25±1.29 cm/s at 28 days of life; P =.081). The E/E′ ratio differed between the no‐bronchopulmonary‐dysplasia (7.21±1.85) and mild‐bronchopulmonary‐dysplasia groups (9.03±2.56; P =.019) at 1 day of life. The left ventricle myocardial performance index decreased between 1 day of life and 36 postconceptional age in infants without bronchopulmonary dysplasia and those with mild bronchopulmonary dysplasia, but not in those with severe bronchopulmonary dysplasia. Conclusion E/A and E/E′ ratios are the most sensitive indicators of impaired left ventricle diastolic function in preterm infants with bronchopulmonary dysplasia.