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Assessment of Impact of Weight Loss on Left and Right Ventricular Functions and Value of Tissue Doppler Echocardiography in Obese Patients
Author(s) -
Yuksel Isa Oner,
Akar Bayram Nihal,
Koklu Erkan,
Ureyen Cagin Mustafa,
Kucukseymen Selcuk,
Arslan Sakir,
Bozkurt Engin
Publication year - 2016
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.13185
Subject(s) - isovolumetric contraction , cardiology , medicine , tissue doppler echocardiography , diastole , doppler echocardiography , weight loss , doppler imaging , doppler effect , ventricular function , diastolic function , obesity , blood pressure , physics , astronomy
Objective In our study, we aimed to evaluate the effect of weight loss on left and right ventricular functions in obese patients. Methods Thirty patients with a BMI greater than 30 kg/m 2 and without any exclusion criteria were included in the study. Left ventricular systolic and diastolic functions were assessed with conventional and tissue Doppler echocardiography ( TDE ). At the end of 3 months, echocardiographic examination was repeated in patients with weight loss for cardiac function evaluation and it was compared to the baseline echocardiographic parameters. Results At the end of 3 months of weight loss period, conventional Doppler echocardiography revealed an improvement in diastolic functions with an increase in mitral E‐wave, a decrease in mitral A‐wave and an increase in E/A ratio. Deceleration time and isovolumetric relaxation time were ascertained shortened and Tei index decreased. TDE showed an increase in left ventricular lateral wall systolic wave (Sm) and E‐wave velocity (Em). Mitral septal annular isovolumetric acceleration time ( IVA ), Sm and Em, were found to be increased, whereas Tei index was ascertained reduced. Right ventricular tissue Doppler examination following weight loss revealed an increase in RV ‐ IVA , RV ‐Sm, and RV ‐Em, and a decrease in Tei index. Conclusion We disclosed that left ventricular structural changes and diastolic dysfunction occur in obese patients, and by weight loss, these abnormalities may be reversible which we demonstrated both by conventional and TDE . In addition, obesity might impair RV function as well, and we observed an enhancement in right ventricular functions by weight loss.