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Three‐Dimensional Echocardiography in the Evaluation of Right Ventricular Global and Regional Systolic Function in Patients with Atrial Septal Defect before and after Percutaneous Closure
Author(s) -
Kong Dehong,
Cheng Leilei,
Dong Lili,
Pan Cuizhen,
Yao Haohua,
Zhou Daxin,
Shu Xianhong
Publication year - 2016
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.13134
Subject(s) - medicine , cardiology , ejection fraction , percutaneous , body surface area , heart failure
Objective To evaluate right ventricular ( RV ) global and regional systolic function in patients with atrial septal defect ( ASD ) before and after percutaneous closure using real time three‐dimensional echocardiography ( RT 3 DE ). Methods RT 3 DE was performed in 81 patients with ASD within 24 hours before and after percutaneous closure to obtain RV global and regional ejection fraction ( EF ) in three compartments (inflow, body, and outflow). RV fractional area change ( FAC ), tricuspid annular plane systolic excursion ( TAPSE ), peak tricuspid systolic velocity (S), and pulmonary vascular resistance ( PVR ) were recorded. Forty matched normal adults were included as controls. Results When compared with controls, RV global and regional EF were decreased in preclosure patients (P < 0.001). FAC was lower while TAPSE and S were higher in preclosure patients than in controls (P < 0.05). After closure, RV systolic function parameters were all reduced (P < 0.001). Regional EF in the body compartment was the lowest among the three compartments in ASD patients (P < 0.05). Procedural percentage changes of RV global EF and regional EF in the inflow compartment were lower than those of two‐dimensional systolic function parameters (P < 0.05). RV global and regional EF in the inflow compartment were negatively correlated with PVR in patients after closure (r = −0.601, −0.543, P < 0.001). Conclusions RV global and regional systolic functions are impaired in open and closed ASD . RT 3 DE ‐derived systolic function parameters are negatively correlated with RV after load. RT 3 DE has potential value in the evaluation of RV systolic function in patients with ASD .