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Utility of Real Time 3D Echocardiography for the Assessment of Left Ventricular Mass in Patients with Hypertrophic Cardiomyopathy: Comparison with Cardiac Magnetic Resonance
Author(s) -
Avegliano Gustavo P.,
Costabel Juan P.,
Asch Federico M.,
Sciancalepore Agustina,
Kuschnir Paola,
Huguet Marina,
TobonGomez Catalina,
Frangi Alejandro F.,
Ronderos Ricardo
Publication year - 2016
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.13096
Subject(s) - hypertrophic cardiomyopathy , medicine , cardiac magnetic resonance , cardiology , gold standard (test) , magnetic resonance imaging , cardiac magnetic resonance imaging , cardiomyopathy , population , linear correlation , radiology , nuclear medicine , heart failure , mathematics , statistics , environmental health
and objectives Patients with hypertrophic cardiomyopathy ( HCM ) have irregular ventricular shapes with small and sometimes obliterated cavities at end‐systole that affect the quantification of left ventricular mass ( LVM ) by conventional methods, such as M‐mode or two‐dimensional echocardiography. The goal of this study was to validate the use of real time three‐dimensional echocardiography ( RT 3 DE ) to quantify LVM using cardiac magnetic resonance imaging ( CMR ) as a reference, in a large population of patients with different types of HCM . Methods Forty‐eight consecutive patients with HCM had a complete transthoracic examination and CMR performed within 7 days. LVM was calculated by M‐mode and RT 3 DE and compared to CMR that served as gold standard. Results Left ventricular mass calculated by RT 3 DE was 195 ± 41 g and 187 ± 49 g by CMR . The correlation between the two methods was moderate, with a Lin index of 0.63 and good linear correlation (r = 0.63, P < 0.0001). The correlation was high when RT 3 DE was of high or adequate image quality. The correlation between LVM by M‐mode and CMR was poor. Conclusion Three‐dimensional echocardiography is an accurate method for the quantification of LVM in patients with different subtypes of HCM that is in better agreement with CMR reference values than M‐mode measurements.