Premium
Comparison between Regional and Local Pulse‐Wave Velocity Data
Author(s) -
Simova Iana,
Katova Tzvetana,
Santoro Ciro,
Galderisi Maurizio
Publication year - 2016
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12985
Subject(s) - pulse wave velocity , medicine , cardiology , cutoff , gold standard (test) , carotid arteries , blood pressure , physics , quantum mechanics
Background Gold standard for pulse‐wave velocity ( PWV ) measurement is determination of the carotid‐femoral cfPWV, reflecting regional aortic PWV . Nevertheless, in several echocardiographic laboratories, PWV is measured locally, most commonly at the common carotid artery ( CCA ). The aim of this study was to compare regional and local PWV values in healthy volunteers. Methods The study population consisted of 22 prospectively enrolled healthy subjects, mean age 38.7 ± 11.1 years, 50% male. For regional PWV measurement, we evaluated cf PWV with a standard echo scanner. Regional PWV was measured at the CCA , with semiautomated dedicated software (MyLab, EsaOte, Italy). Results cf PWV and local PWV values correlated significantly with high Pearson correlation coefficient (0.62, P = 0.002). Mean regional cfPWV (9.29 ± 3.73 m/s), however, was significantly higher than mean local PWV value (5.96 ± 1.08 m/s) (P < 0.001). The difference persisted in the subgroup analysis using different cf PWV cutoff values (10, 9, 8, and 7 m/s), except for subjects with cf PWV ≤7 m/s, where regional and local PWV values were similar. Conclusion In a group of healthy volunteers, regional and local PWV values showed a good correlation. However, regional PWV was significantly higher than local PWV . These findings should be carefully taken into account when using this technique in the clinical setting.