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Association of Mitral Annular Calcification with Left Ventricular Mechanics: A Speckle Tracking Study
Author(s) -
Gökdeniz Tayyar,
Boyaci Faruk,
Hatem Engin,
Bektaş Hüseyin,
Kalaycıoğlu Ezgi,
Gürsoy Mustafa Ozan,
Aykan Ahmet Çağrı,
Yıldız Banu Şahin,
Altıntaş Bernas
Publication year - 2015
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12861
Subject(s) - cardiology , medicine , diastole , speckle tracking echocardiography , systole , mass index , body mass index , heart failure , blood pressure , ejection fraction
Background Mitral annular calcification ( MAC ) is a common echocardiographic finding in clinical practice and is associated with cardiovascular risk factors and atherosclerosis. However, data regarding left ventricular ( LV ) functions are lacking. We aimed to evaluate the relationship between MAC and LV mechanical functions with the utility of two‐dimensional speckle tracking echocardiography (2DSTE). Methods The study involved 91 patients with MAC and 48 control subjects. Mitral annular thickness of 1–2 mm was reported as mild, 2–5 mm as moderate, and >5 mm as severe MAC . All patients underwent 2D echocardiography. Results MAC was observed in 91 (65.5%) patients. Of LV diastolic parameters, E/Em ratio, LAVI , LV mass index, and t‐ LV UR were increased. Of LV systolic parameters, GLS and Sm were decreased, whereas Ar, Ar‐rate systole , peak LV twist, peak LV twist rate, LV ‐tor, and MPI were increased, which were all correlated with presence and severity of MAC . Multivariate linear regression analysis showed that LV mass index (β = 0.225, P = 0.012), t‐ LV UR (β = 0.370, P < 0.001), LV mass index (β = 0.183, P = 0.025), MPI (β = 0.288, P < 0.001), and GLS (β = −0.385, P < 0.001) were significantly associated with MAC severity. Conclusion The presence and severity of MAC is associated with impaired LV systolic and diastolic functions. Therefore, preventive strategies might be taken in patients with MAC to avoid LV systolic and diastolic dysfunction.