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Left Atrial Asynchrony and Mechanical Function in Patients with Mitral Stenosis before and Immediately after Percutaneous Balloon Mitral Valvuloplasty: A Real Time Three‐Dimensional Echocardiography Study
Author(s) -
Deng Yan,
Guo Shenglan,
Su Hongyue,
Wang Qian,
Tan Zhen,
Wu Ji,
Zhang Di
Publication year - 2015
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12645
Subject(s) - cardiology , medicine , asynchrony (computer programming) , mitral valve , percutaneous , stenosis , mitral valve stenosis , balloon , end systolic volume , heart rate , stroke volume , blood pressure , computer network , asynchronous communication , computer science
Objective This study evaluated the feasibility of assessing left atrium ( LA ) function and asynchrony in patients with rheumatic mitral stenosis ( MS ) before and immediately after percutaneous balloon mitral valvuloplasty ( PBMV ) by real time three‐dimensional echocardiography (RT3DE). Methods Thirty patients with rheumatic MS who underwent PBMV and 30 controls were enrolled. RT3DE was used to measure LA volume and function, the standard deviation of time to the minimal systolic volume divided into 16 segments, 12 segments, or 6 segments (Tmsv 16‐ SD , Tmsv 12‐ SD , Tmsv 6‐ SD ), and the maximum differences (Tmsv 16‐Dif, 12‐Dif, 6‐Dif) in RT3DE derived values in MS patients before and 2 days after PBMV were obtained and compared with those of normal controls. The associations between the LA asynchrony and heart volume, function, mitral valve area ( MVA ), maximum mitral valve gradient (MVG max ), mean mitral valve gradient ( MVG mean), and mean LA pressure ( MLAP ) were investigated. Results Left atrium asynchrony indexes were significantly larger, and LA function parameters were significantly lower in the MS group than in the controls (P < 0.05 for all). Of all the LA asynchrony indexes, LA Tmsv16‐ SD was most significantly correlated with the LA volume and function parameters, MVG max , MVG mean , and MLAP (P < 0.05 for all). LA asynchrony indexes and LA volume significantly deceased, and LA function significantly increased post‐ PBMV (P < 0.05). Conclusion Real time three‐dimensional echocardiography is a reliable and reproducible method to quantify LA function and asynchrony. RT3DE revealed a significant, early improvement in LA function and asynchrony in MS patients after PBMV .