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New Universal Strain Software Accurately Assesses Cardiac Systolic and Diastolic Function Using Speckle Tracking Echocardiography
Author(s) -
Kolias Theodore J.,
Hagan Peter G.,
Chetcuti Stanley J.,
Eberhart Diane L.,
Kline Nicole M.,
Lucas Sean D.,
Hamilton James D.
Publication year - 2014
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12512
Subject(s) - biplane , ejection fraction , medicine , dicom , diastole , strain rate , receiver operating characteristic , cardiology , ultrasound , speckle tracking echocardiography , strain (injury) , speckle pattern , diastolic function , nuclear medicine , radiology , artificial intelligence , heart failure , blood pressure , computer science , materials science , metallurgy , composite material
Background We have developed new universal strain software ( USS ) that can be used to perform speckle tracking of any Digital Imaging and Communications in Medicine ( DICOM ) image, regardless of the ultrasound system used to obtain it. Methods Fifty patients prospectively underwent echocardiography immediately prior to cardiac catheterization. Biplane peak global longitudinal strain ( GLS ), peak systolic longitudinal strain rate ( SSR ), peak early diastolic longitudinal strain rate ( DSR ), and peak early diastolic circumferential strain rate ( DCSR ) were determined using conventional strain software ( CSS ) that uses raw data, and using the new USS applied to DICOM images. Results Universal strain software correlated with CSS for GLS (r = 0.78, P < 0.001), SSR (r = 0.78, P < 0.001), DSR (r = 0.54, P < 0.001), and DCSR (r = 0.43, P = 0.019). GLS and SSR using USS correlated with left ventricular ejection fraction ( LVEF ) (r = −0.67 and −0.71, respectively) as well as using CSS (r = −0.66 and −0.71). Patients with diastolic dysfunction had significantly lower DSR (0.61 vs. 0.87/sec, P = 0.02) and DCSR (0.89 vs. 1.23/sec, P = 0.03), and less negative GLS (−10.8 vs. −16.1%, P = 0.002) using USS in all patients, as well as among those with LVEF ≥ 50%. Receiver‐operating characteristic ( ROC ) analysis for detection of diastolic dysfunction revealed a sensitivity and specificity of 82% and 83% for DCSR < 1.09/sec (area under the curve [ AUC = 0.80]) and 85% and 83% for GLS > −13.7% ( AUC = 0.84) using USS . Conclusion Universal strain software can be used to accurately assess LV systolic and diastolic function using speckle tracking echocardiography.