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Prevalence and Spectrum of Conditions Associated with Severe Tricuspid Regurgitation
Author(s) -
Ong Kevin,
Yu Gan,
Jue John
Publication year - 2014
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12420
Subject(s) - medicine , atrial fibrillation , regurgitation (circulation) , etiology , cardiology , cohort , transthoracic echocardiogram , tricuspid valve , retrospective cohort study
Background Data regarding the prevalence and spectrum of conditions associated with severe tricuspid regurgitation ( TR ) are limited to small cohorts. Methods We retrospectively identified all patients with severe native tricuspid valve regurgitation in a large echocardiogram database between January 2004 and December 2010. Patients were classified into 1 of 3 groups based on the echocardiogram results: (1) organic TR ; (2) functional TR ; and (3) idiopathic TR . Results Severe TR was identified in 768 (1.2%, 72 ± 16 years, 64.3% females) of 63, 472 consecutive patients referred for transthoracic echocardiography. The conditions associated with severe TR could be established in 91% of patients. The remaining 9% were classified as idiopathic severe TR with these patients being older (78 ± 10 years) and having a higher frequency of atrial fibrillation (63.8%) compared to patients with organic (65 ± 22 years; 31%) or functional severe TR (73 ± 16 years; 47.8%). Overall, organic severe TR was identified in 11.3% of all cases. Functional severe TR occurred in 79.7% of the overall cohort and was related to pulmonary hypertension and/or left‐sided heart disease. Conclusion Severe TR occurred with a prevalence of 1.2% in our patients referred for echocardiography and was more common in females. Functional severe TR was the most common etiology with only a minority of cases secondary to organic severe TR . Idiopathic severe TR was found in a small proportion of patients who were older and more likely to have atrial fibrillation.