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Severe Mitral Regurgitation after Radiotherapy
Author(s) -
Cozzarín Alberto,
Cianciulli Tomás F.,
Saccheri María C.,
Lax Jorge A.,
Simonetti Mario E.,
Zappi Andrea,
Laguens Rubén P.
Publication year - 2014
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12409
Subject(s) - medicine , radiation therapy , mitral regurgitation , regurgitation (circulation) , cardiology , pulmonary hypertension , heart failure , mitral valve , radiology
We present the case of a 69‐year‐old patient with a history of gynecological neoplasia and a pulmonary metastasis, who in 1996 underwent chemotherapy and mediastinal radiotherapy followed by cancer remission. Ten years later she presented with heart failure and her Doppler echocardiogram showed severe mitral regurgitation with pulmonary hypertension. In 2011, she underwent a mitral valve replacement with a biological prosthesis and the pathology exam revealed valve damage consistent with radiotherapy‐induced changes. This unusual mechanism of mitral regurgitation can be demonstrated clearly by echocardiography and should be disseminated among cardiology physicians and in patients who have survived for long periods after radiotherapy, it is important to remember that cardiac complications may indeed occur, and the treating physician is responsible for detecting them.