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Catheterization Diastolic Pressures Correlate with Diastolic Dyssynchrony in Patients with Single Right Ventricles
Author(s) -
Stiver Corey,
Gokhale Janaki,
Husain Nazia,
Nicholson Lisa,
Cordier Joyce,
Van Lente Lindsey,
Holzer Ralf J.,
Cua Clifford L.
Publication year - 2014
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12373
Subject(s) - qrs complex , cardiology , medicine , diastole , ventricle , cardiac catheterization , blood pressure
Introduction Diastolic dyssynchrony has correlated with pulmonary capillary wedge pressures in patients with normal cardiac anatomy. No data exist in single right ventricle ( sRV ) patients. Goal of this study was to determine if diastolic dyssynchrony in sRV patients correlates with ventricular end‐diastolic pressures ( VEDP ). Methods Tissue Doppler imaging ( TDI ) and strain rate ( SR ) analysis of sRV patients undergoing catheterization were performed. Time interval from onset of QRS to peak TDI e'‐wave was obtained. Differences in intervals were calculated: QRS ( RV ) − QRS ( IVS ) and QRS ( RV ) − QRS ( LV ). Time interval from onset of QRS to peak strain rate early diastolic wave ( SR e) was obtained for the 6 segment model sRV . Standard deviation of the 6 SR e time intervals was calculated. Correlation of VEDP with timing intervals was analyzed. Results Forty sRV patients were evaluated. Age was 2.8 ± 3.5 years. Catheterization VEDP of the sRV was 9.3 ± 3.9 mmHg (median 8 mmHg range 4–24 mmHg). QRS ( RV ) − QRS ( IVS ) was 22.3 ± 18.1 msec and QRS ( RV ) − QRS ( LV ) was 23.7 ± 19.0 msec. SR e standard deviation of the sRV was 61.6 ± 23.9 msec. There was no significant correlation with VEDP and QRS ( RV ) − QRS ( IVS ) (r = 0.1, P = NS ) or with QRS ( RV ) − QRS ( LV ) (r = 0.2, P = NS ). There was a significant correlation of VEDP with the SR e standard deviation value (r = 0.4, P < 0.05). Conclusion Diastolic dyssynchrony correlated with VEDP in patients with sRV physiology. Future studies are needed to determine the significance of these findings.