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Advantages of Real Time Three‐Dimensional Echocardiography in the Assessment of Right Ventricular Volumes and Function in Patients with Pulmonary Hypertension Compared with Conventional Two‐Dimensional Echocardiography
Author(s) -
Di Bello Vitantonio,
Conte Lorenzo,
Delle Donne Maria Grazia,
Giannini Cristina,
Barletta Valentina,
Fabiani Iacopo,
Palagi Caterina,
Nardi Carmela,
Dini Frank Lloyd,
Marconi Letizia,
Paggiaro Pierluigi,
Palla Antonio,
Marzilli Mario
Publication year - 2013
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12137
Subject(s) - medicine , cardiology , pulmonary hypertension , ejection fraction , doppler imaging , ventricular function , diastole , muscle hypertrophy , right ventricular hypertrophy , end systolic volume , doppler echocardiography , pulmonary artery , stroke volume , blood pressure , heart failure
Background In recent years, right ventricular ( RV ) function has acquired greater relevance as a clinical and prognostic marker in many physiopathological conditions. The study aims to point out the value of real time three‐dimensional echocardiography ( RT 3 DE ) and tissue D oppler imaging ( TDI ) in the evaluation of patients affected by pulmonary hypertension ( PH ), compared with conventional two‐dimensional (2D) echocardiography. Methods We enrolled 44 subjects affected by PH who underwent 2D and Doppler echocardiography, RT 3D Echocardiography and TDI evaluation of the RV , and a healthy control group. PH itself can induce severe functional and structural abnormalities of the RV , such as RV hypertrophy, RV dilation, and RV systolic and diastolic dysfunction. Results In this study, RV FAC , and TAPSE showed marked alterations in patients with PH compared to the control group (C): ( RVFAC : [ PH ] 0.29 ± 0.07 vs. [C] 0.49 ± 0.05%, P < 0.0001; TAPSE : [ PH ] 15.3 ± 3.2 vs. [C] 21.1 ± 2.6 mm, P > 0.0001). The 3D RV end‐diastolic volume was significantly higher in PH than in C ( PH ) (138.7 ± 25.3 vs. [C] 82.8 ± 12.5 mL, P < 0.0001] as well as 3D RV end‐systolic volume ( PH ) (97.6 ± 21.5 vs. [C] 39.3 ± 9.5 mL, P < 0.0001). The 3D RV ejection fraction ( EF ) was significantly lower in the pulmonary hypertension group than in healthy subjects (31.8 ± 6.8 vs. [C] 52.5 ± 4.7%, P < 0.0001). Conclusions In patients with PH , evaluation of the RV diastolic and systolic volume and EF by RT 3 DE has shown a higher discriminating power in comparison, respectively, with 2 DRV diastolic area and the relative fractional area changes.