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Viewpoint: The ENIGMAS Trial – When Should We Treat Patients with Moderate Aortic Stenosis?
Author(s) -
Mischie Alexandru Nicolae,
Andrei Catalina Liliana,
Sinescu Crina
Publication year - 2013
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12080
Subject(s) - stenosis , medicine , cardiology , magnetic resonance imaging , valvular heart disease , cardiac magnetic resonance imaging , population , disease , cardiac magnetic resonance , clinical trial , radiology , environmental health
Aortic stenosis ( AS ) is the most frequent valvular heart disease encountered in our daily practice. Although there are clear guidelines for severe AS management, cardiologists often have few treatment options for patients with moderate AS ; however, there is higher mortality in this patient subgroup versus an age‐matched population. The authors reviewed all of the studies on moderate AS , summarized the factors that increase disease progression and discussed an ideal trial design to prospectively evaluate AS progression factors using modern cardiology tools such as strain and magnetic resonance imaging.