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Impact of TAVI on Mitral Regurgitation: A Prospective Echocardiographic Study
Author(s) -
Giordana Francesca,
Capriolo Michele,
Frea Simone,
Marra Walter Grosso,
Giorgi Mauro,
Bergamasco Laura,
Omedè Pier Luigi,
Sheiban Imad,
D'Amico Maurizio,
Bovolo Virginia,
Salizzoni Stefano,
Torre Michele,
Rinaldi Mauro,
Marra Sebastiano,
Gaita Fiorenzo,
Morello Mara
Publication year - 2013
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/echo.12050
Subject(s) - medicine , mitral regurgitation , cardiology , prospective cohort study , regurgitant fraction , etiology , mitral valve , regurgitation (circulation) , nuclear medicine , heart failure , ejection fraction
Objective: This study aims to assess changes in mitral regurgitation ( MR ) severity after transcatheter aortic valve implantation ( TAVI ). Background: Existing data on MR after TAVI are contradictory. Methods: Thirty‐five patients with MR graded ≥ 2+ were followed after undergoing TAVI with either the E dwards S apien or CoreValve device. Echocardiography was performed the week before and 3 months after the procedure. MR was graded on a scale of 0 to 4+, classified as organic or functional, and the effective regurgitant orifice area ( EROA ) and MR index were calculated. Results: At baseline, MR was graded 4+ in 4 (11.4%) patients, 3+ in 10 (28.6%), and 2+ in 21 (60%). At follow‐up, MR was graded at 3+ in 4 (11.4%) patients, 2+ in 8 (22.9%), and 1+ in 19 (54.3%); 4 (11.4%) exhibited no MR . EROA (24.4 ± 11.5 mm 2 pre‐ TAVI vs. 11.2 ± 10.3 mm 2 post‐ TAVI , P < 0.001) and MR index (1.9 ± 0.3 pre‐ TAVI vs. 1.3 ± 0.7 post‐ TAVI , P < 0.001) were reduced with TAVI , independent of the etiology. MR decreased by at least 1 grade in 28 (80%) patients, with a reduction ≥2 grades in 10 (28.6%) patients; no patient showed a worsened condition. Subgroup analyses showed that the reduction in MR was significant in patients treated with the E dwards S apien device but not in patients treated with the C ore V alve device. Conclusions: This multiparametric echocardiographic evaluation showed that MR improved significantly after TAVI and that this result may be related to the type of valve implanted.