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Predicting hypertension among Korean cancer survivors: A nationwide population‐based study
Author(s) -
Kim Y.H.,
Cho K.H.,
Kim K.H.,
Ryu E.J.,
Han K.D.,
Kim J.S.
Publication year - 2018
Publication title -
european journal of cancer care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 67
eISSN - 1365-2354
pISSN - 0961-5423
DOI - 10.1111/ecc.12803
Subject(s) - medicine , nomogram , prehypertension , diabetes mellitus , comorbidity , decile , obesity , population , odds ratio , incidence (geometry) , overweight , logistic regression , demography , blood pressure , endocrinology , environmental health , statistics , mathematics , sociology , optics , physics
Hypertension is the most common comorbidity among cancer survivors, although there is no model for predicting hypertension in this population. Therefore, we developed a model for predicting hypertension using data from 6,480 Korean cancer survivors who were ≥20 years old. The odds ratios ( OR s) for hypertension were calculated using stepwise logistic regression analyses, and a nomogram was generated to predict hypertension. Hypertension was independently associated with an age of ≥65 years ( OR : 3.058), male gender ( OR : 1.195), obesity ( OR : 1.998), prehypertension ( OR : 2.06), dyslipidaemia ( OR : 2.011) and diabetes mellitus ( OR : 2.297). Each variable in the nomogram was assigned a specific number of points, and the total score (range: 0–400) was used to obtain a value for predicting hypertension. The estimated prevalence of hypertension increased when the total nomogram score exceeded the sixth decile (total points: 128; p for trend <.001). Therefore, among Korean cancer survivors, hypertension was significantly associated with an age of >65 years, male gender, obesity, and having various comorbidities (e.g., prehypertension, dyslipidaemia and diabetes mellitus). Furthermore, our nomogram could predict the incidence of hypertension, and the sixth decile of the total nomogram score predicted an increased risk of hypertension.