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Relationship of physical activity with physical function and health‐related quality of life in patients having undergone allogeneic haematopoietic stem‐cell transplantation
Author(s) -
Morishita S.,
Kaida K.,
Yamauchi S.,
Wakasugi T.,
Ikegame K.,
Ogawa H.,
Domen K.
Publication year - 2017
Publication title -
european journal of cancer care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 67
eISSN - 1365-2354
pISSN - 0961-5423
DOI - 10.1111/ecc.12669
Subject(s) - medicine , haematopoiesis , stem cell , transplantation , quality of life (healthcare) , physical activity , gerontology , physical therapy , microbiology and biotechnology , nursing , biology
In this study, we investigated the differences in physical activity before and after transplantation, and the relationship between physical activity and physical function and health‐related quality of life ( QOL ) in 30 patients who underwent allogeneic haematopoietic stem cell transplantation (allo‐ HSCT ). Duration and intensity of physical activity were quantified using a three‐dimensional accelerometer. Physical function was quantified by handgrip and knee‐extensor strength, with the 6‐minute walk test (6 MWT ) used as a measure of exercise capacity. Health‐related QOL was assessed using the 36‐item Short‐Form Health Survey. The proportion of daily activities performed at an intensity >3.0 metabolic equivalents ( MET s) increased significantly after allo‐ HSCT ( p < .05). Daily activity time performed at an intensity of 1.6–2.9 MET s significantly correlated only with left knee strength ( p < .05). In contrast, the total number of daily steps and the proportion of activity performed at 1.6–2.9 MET s and >3.0 MET s were positively correlated with the 6 MWT ( p < .05). Additionally, physical functioning and general health subscales in health‐related QOL positively correlated with daily activities performed at >3.0 MET s ( p < .05). Physical activity was associated with 6 MWT and health‐related QOL . These findings have implications for rehabilitation planning for patients undergoing allo‐ HSCT .