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Neodymium yttrium‐aluminium‐garnet laser resection significantly improves quality of life in patients with malignant central airway obstruction due to lung cancer
Author(s) -
Zaric B.,
Kovacevic T.,
Stojsic V.,
Sarcev T.,
Kocic M.,
Urosevic M.,
Kalem D.,
Perin B.
Publication year - 2015
Publication title -
european journal of cancer care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 67
eISSN - 1365-2354
pISSN - 0961-5423
DOI - 10.1111/ecc.12256
Subject(s) - medicine , quality of life (healthcare) , lung cancer , nausea , vomiting , nd:yag laser , surgery , stage (stratigraphy) , laser , paleontology , physics , nursing , optics , biology
Neodymium yttrium‐aluminium‐garnet ( Nd : YAG ) laser resection is one of the mostly used interventional pulmonology techniques for urgent desobstruction of malignant central airway obstruction ( CAO ). The major aim of this trial was to evaluate potential influence of Nd : YAG laser resection on overall quality of life ( QoL ) in patients with central lung cancer. Patients with malignant CAO scheduled for N d : YAG laser resection were prospectively recruited in the trial. All patients were given E uropean O rganization for R esearch and T reatment, Q uality of L ife questionnaire ( EORTC QLQ ‐30 v.3) before the procedure and approximately 2 weeks after the treatment. There were 37 male and 10 female patients, average age 54 ± 10 years. Most common tumour type was adenocarcinoma diagnosed in 51% of patients. Majority of patients were diagnosed in stage IIIB (53.2%) and stage IV (25.5%). Most common E astern C ooperative O ncology G roup performance status was 1 (72.3%). Nd : YAG laser resection significantly improved ( P < 0.0001) QoL and overall health according to EORTC QLQ ‐30. However, in some of the questions dealing with nausea, vomiting, diarrhoea, constipation, family life, social activities and financial situation, we did not observe statistically significant improvement. Nd : YAG laser resection of malignant CAO significantly improves QoL and overall health in patients with lung cancer.