Premium
Safety and feasibility of physical therapy in cytopenic patients during allogeneic haematopoietic stem cell transplantation
Author(s) -
Morishita S.,
Kaida K.,
Setogawa K.,
Kajihara K.,
Ishii S.,
Ikegame K.,
Kodama N.,
Ogawa H.,
Domen K.
Publication year - 2013
Publication title -
european journal of cancer care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 67
eISSN - 1365-2354
pISSN - 0961-5423
DOI - 10.1111/ecc.12027
Subject(s) - medicine , cytopenia , quality of life (healthcare) , transplantation , stem cell therapy , stem cell , physical therapy , bone marrow , nursing , biology , genetics
Safety and feasibility of physical therapy in cytopenic patients during allogeneic haematopoietic stem cell transplantation This study aimed to investigate the safety and feasibility of physical therapy in cytopenic patients undergoing allogeneic haematopoietic stem cell transplantation (allo‐ HSCT ), and to investigate the effect of physical therapy on physiological functions and quality of life ( QOL ) in allo‐ HSCT patients. The study cohort included 321 patients who underwent allo‐ HSCT . To investigate the safety and feasibility of physical therapy during cytopenia, patients were assigned to the physical therapy group ( n = 227) or the control group ( n = 94). To determine the effects of physical therapy, patients were divided according to the frequency with which they underwent physical therapy ( n = 51 per group). Handgrip strength, knee extensor strength and a 6‐min walk test were used as measures of physiological function. Short‐Form 36 was used to assess QOL . The physical therapy group had higher rate of achieving engraftment and lower death rate than the control group ( P < 0.05). After HSCT , the high‐frequency physical therapy group showed significantly less decline than the low‐frequency physical therapy group with respect to physical functioning of QOL ( P < 0.01). Physical therapy is quite beneficial and can be performed safely and feasibly in cytopenic patients during allo‐ HSCT .