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Microdermabrasion assisted delivery of glycolic acid 70% peel for the treatment of melasma in dark‐skinned patients
Author(s) -
AbdelMotaleb Amira A.,
Bakr Radwa M.
Publication year - 2021
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.15025
Subject(s) - melasma , medicine , glycolic acid , dermatology , clinical efficacy , surgery , lactic acid , biology , bacteria , genetics
Melasma is a disfiguring dermatologic condition and its treatment is still considered a challenge. To evaluate the efficacy and safety of microdermabrasion (MDA) combined with glycolic acid 70% (GA70%) peel versus GA70% alone in treating melasma in dark‐skinned patients. This study included 30 female patients (skin type IV and V) with melasma. After cleansing the face, 3 passes of MDA were done on one side of the face. Then, GA70% was applied to the whole face in 1–2 uniform passes. Melasma area and severity index (MASI), modified MASI and hemi‐MASI scores were used to assess the outcome. A significant decline of the mean MASI, mMASI and both hemi‐MASI scores following treatment (p value = 0.000 for each). Furthermore, the hemi‐MASI score on the MDA/GA70% treated side showed significantly greater decrease than the hemi‐MASI score on GA70% treated side (p value = 0.041). MDA enhanced the improvement of GA70% peel effectively and safely.