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A case of orofacial granulomatosis evolving into Melkersson Rosenthal syndrome in a child treated with a steroid free regimen of Clofazimine and Minocycline
Author(s) -
Sachdeva Soumya,
Raina Alok,
Sardana Kabir,
Malhotra Purnima
Publication year - 2021
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.15009
Subject(s) - clofazimine , medicine , melkersson–rosenthal syndrome , minocycline , regimen , dermatology , etiology , surgery , pediatrics , leprosy , antibiotics , microbiology and biotechnology , biology
Orofacial granulomatosis (OFG) is a rare disorder with varied etiological, immunological and infectious mechanisms implicated and is believed to be a umbrella term which includes Melkersson Rosethal syndrome (MRS). We describe a 17 year old female who was diagnosed with OFG and was successfully treated with a combination of minocycline and clofazimine without oral steroids with significant improvement within 1 month of therapy.