A case of orofacial granulomatosis evolving into Melkersson Rosenthal syndrome in a child treated with a steroid free regimen of Clofazimine and Minocycline | Zendy

Sachdeva Soumya | Zendy; Raina Alok | Zendy; Sardana Kabir | Zendy; Malhotra Purnima | Zendy

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A case of orofacial granulomatosis evolving into Melkersson Rosenthal syndrome in a child treated with a steroid free regimen of Clofazimine and Minocycline

Author(s) -

Sachdeva Soumya,

Raina Alok,

Sardana Kabir,

Malhotra Purnima

Publication year - 2021

Publication title -

dermatologic therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.595

H-Index - 68

eISSN - 1529-8019

pISSN - 1396-0296

DOI - 10.1111/dth.15009

Subject(s) - clofazimine , medicine , melkersson–rosenthal syndrome , minocycline , regimen , dermatology , etiology , surgery , pediatrics , leprosy , antibiotics , microbiology and biotechnology , biology

Orofacial granulomatosis (OFG) is a rare disorder with varied etiological, immunological and infectious mechanisms implicated and is believed to be a umbrella term which includes Melkersson Rosethal syndrome (MRS). We describe a 17 year old female who was diagnosed with OFG and was successfully treated with a combination of minocycline and clofazimine without oral steroids with significant improvement within 1 month of therapy.

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