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Diagnosis and treatment of melanoma bone metastasis: A multidisciplinary approach
Author(s) -
Caldaria Antonio,
Giuffrida Roberta,
di Meo Nicola,
Massari Leo,
Dianzani Caterina,
Cannavò Serafinella Patrizia,
Degrassi Ferruccio,
Casablanca Edoardo,
Zalaudek Iris,
Conforti Claudio
Publication year - 2020
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.14193
Subject(s) - medicine , melanoma , radiation therapy , metastasis , bone metastasis , quality of life (healthcare) , surgery , oncology , radiology , cancer , cancer research , nursing
Bone is the fourth most common site of melanoma metastasis after lung, liver, and brain. Melanoma bone metastases typically occur in patients who already have widespread metastases in other organs. Current available approaches for bone metastases from melanoma include chemotherapy, radiotherapy, biological therapy, combination therapy, and surgery. In this narrative review, we describe the management of patients affected by melanoma bone metastases, discussing the diagnostic and treatment approaches as well as their impact on survival and quality of life. Despite the fact that clinical and surgical trials will be required to determine the most appropriate treatment, we do expect a newer and more important role of multidisciplinary approach in the management of melanoma patients with bone metastases in the next future.