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Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine
Author(s) -
Schwartz Robert A.,
Janniger Camila K.
Publication year - 2020
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.13380
Subject(s) - hydroxychloroquine , medicine , acute generalized exanthematous pustulosis , dermatology , erythema , drug eruption , drug , disease , covid-19 , pathology , pharmacology , infectious disease (medical specialty)
A severe cutaneous drug reaction resembling acute generalized exanthematous pustulosis resulting from ingestion of hydroxychloroquine has been documented. It is distinguishable by its longer incubation period, more varied morphology with initially urticarial and later targetoid and arcuate plaques, recalcitrance to therapy and longer duration. Given the anticipated surge in the use of hydroxychloroquine due to its reported benefits in those with coronavirus disease 2019, specific recognition of this entity is pivotal. We delineate it as generalized pustular figurate erythema.