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A case of Jarisch–Herxheimer reaction in candidiasis treated with systemic fluconazole
Author(s) -
Muscianese Marta,
Magri Francesca,
Pranteda Giulia,
Pranteda Guglielmo
Publication year - 2020
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.13244
Subject(s) - fluconazole , medicine , syphilis , dermatology , latent syphilis , human immunodeficiency virus (hiv) , immunology , antifungal
Jarisch–Herxheimer reaction (JHR) is an acute and self‐limited condition, which commonly occurs after treatment for spirochetal infections. Probably, it corresponds to a transient immunological reaction to endotoxin‐like products released from the microorganism during the therapy. For this reason, JHR may be associated with many other infectious diseases besides syphilis. Here, we report a case of a patient affected by extended cutaneous candidiasis diagnosed by culture examination; a JHR occurred after an accidental overdose of oral fluconazole.