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Gold nanoshell‐mediated photothermal therapy for acne vulgaris
Author(s) -
Park Kui Young,
Han Hye Sung,
Hong Ji Yeon,
Seo Seong Jun,
Lee Sang Ju
Publication year - 2019
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.13189
Subject(s) - acne , medicine , nanoshell , photothermal therapy , dermatology , nanotechnology , materials science , nanoparticle
Acne vulgaris, a common and chronic disorder of the pilosebaceous unit, affects up to 85% of adolescent and young adults. Although the current treatment options are effective, they are associated with unwanted side effects, chronicity, relapses, and recurrences. Recently, the Food and Drug Administration approved topical application of gold microparticles for selective photothermolysis to treat acne vulgaris. Here, we report two cases showing the efficacy of gold nanoshell‐mediated photothermal therapy for recurrent acne that were refractory to previous treatments. In both cases, three sessions of photothermal therapy prevented the development of new lesions during a follow‐up period of 3–4 months without causing any adverse effects. The two cases reported here demonstrate the possibility of gold nanoshell‐mediated photothermal therapy as a safe and effective treatment for recurrent acne vulgaris in Asian patients.

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