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Clinical efficacy of paiteling in the treatment of condyloma acuminatum infected with different subtypes of HPV
Author(s) -
Hu Yanqing,
Lu Yan,
Qi Xinyu,
Chen Xuyang,
Liu Kangxing,
Zhou Xianyi,
Yang Yemei,
Mao Zuhao,
Wu Zhong,
Hu Yongxuan
Publication year - 2019
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.13065
Subject(s) - medicine , condyloma acuminatum , anus , human papillomavirus , dermatology , clinical efficacy , external genitalia , disease , gastroenterology , surgery , anatomy
Condyloma acuminatum (CA) is a type of mucosal benign hyperplasia skin disease that is caused by human papillomavirus (HPV) infection, which mainly occurs in the genitalia and anus. The aim of the present study was to explore the clinical efficacy underlying the traditional Chinese medicine paiteling in the treatment of CA via the detection of HPV. One hundred CA patients were enrolled in the current study and were externally treated with paiteling for 5 weeks. HPV subtypes were examined both before the treatment and at 6 months after the treatment. After the external paiteling therapy, 92 cases were cured, and the apparent efficiency was 92.0% (92/100), while 8 cases exhibited recurrence. Before the external paiteling therapy, the numbers of cases of low‐risk, high‐risk, and mixed types of HPV were 40, 35, and 25, respectively. At 6 months after treatment, the numbers of negative cases of low‐risk, high‐risk, and mixed types of HPV were 38, 32, and 20, respectively. The results demonstrated that external paiteling treatment has a good curative effect on the treatment of CA.