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The efficacy of early immunosuppression in a morphea patient complicated with pulmonary interstitial fibrosis
Author(s) -
Chen Binglin,
Xue Meijuan,
Yang Ji,
Li Ming
Publication year - 2019
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.13061
Subject(s) - morphea , medicine , pulmonary fibrosis , immunosuppression , scleroderma (fungus) , dermatology , organ system , connective tissue disease , fibrosis , pathology , autoimmune disease , disease , lichen sclerosus , inoculation
Currently seldom cases have been reported that generalized morphea could accompany with organ dysfunction. However, our study reveals not only morphea could complicate with intranet organ involvements but it may also be the early phase of systemic sclerosis. Furthermore, our therapy challenged the traditional morphea treatment to prove that cyclophosphamide and glucocorticoid are efficient to treat morphea with organ dysfunction.