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Serpentine supravenous hyperpigmentation related to carboplatin and vinorelbine chemotherapy: A case report
Author(s) -
Akyurek Fatma Tuncez,
Sari Nihal,
Ugurluoglu Ceyhan,
Kurtipek Gulcan Saylam
Publication year - 2019
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12981
Subject(s) - medicine , hyperpigmentation , carboplatin , vinorelbine , dermatology , histopathology , chemotherapy , vinblastine , basal (medicine) , pathology , cisplatin , insulin
Serpentine supravenous hyperpigmentation (SSH) is a unique type of chemotherapy‐associated drug eruption, characterized by hyperpigmentation along the superficial venous network. Histopathology reveals an increase in melanin production without destruction of basal cells of the epidermis or dermal inflammatory infiltrate. Herein, we describe a patient who developed SSH after repeated intravenous infusions with carboplatin and vinorelbine; two medications that have been uncommonly reported in association with SSH previously.