Premium
Dermatomyofibroma—A rare mesenchymal tumor with maintained horripilation
Author(s) -
Wollina Uwe,
Schönlebe Jacqueline
Publication year - 2019
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12967
Subject(s) - dermatofibrosarcoma protuberans , medicine , pdgfb , cd34 , mesenchymal stem cell , differential diagnosis , pathology , solitary fibrous tumor , stem cell , microbiology and biotechnology , biology , platelet derived growth factor receptor , receptor , growth factor
Dermatomyofibroma is a rare mesenchymal tumor of skin. The major differential diagnosis is dermatofibrosarcoma protuberans. Both lesions are composed of spindle‐shaped cells which are CD34‐positive. In contrast to the malignant counterpart, the tumor cells in dermatomyofibroma are without any evidence of COL1A1‐PDGFB gene rearrangement. We present a case of axillary dermatomyofibroma in a 31‐year‐old woman. A hitherto undescribed clinical phenomenon is a maintained horripilation in contrast to dermatofibrosarcoma protuberans.