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Local hyperthermia cleared multifarious viral warts in a patient with Cushing's syndrome
Author(s) -
Mu MingHan,
Wang YiNing,
Huang Yu,
Niu XueLi,
Chen HongDuo,
Gao XingHua,
Qi RuiQun
Publication year - 2019
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.12815
Subject(s) - medicine , plantar warts , imiquimod , clearance , dermatology , common warts , hyperthermia , cryotherapy , forehead , eyelid , surgery , urology , human papillomavirus
Abstract A female Cushing's syndrome patient had been suffering from extensive viral warts for months. She was diagnosed with flat warts, common warts and plantar warts. The plantar warts on her right foot were initially treated using local hyperthermia at 44°C for 30 min according to a defined protocol, followed by treatment targeting a common wart on her left thumb. In response to hyperthermia, the flat warts on her eyelid dissipated within 12 weeks, and when combined with a 1 week administration of imiquimod, the common warts and plantar warts completely disappeared within 8 weeks. There were no signs of recurrence and during this treatment her Cushing's syndrome was alleviated. This pioneer trial suggests that local hyperthermia may serve as an effective mean for treating multiple cutaneous warts under the conditions of a systemic immuno‐compromised disease.